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It is one of the best acclaimed paintings in American history: Christina’s World, by Andrew Wyeth. The painting, which hangs in the Museum of Modern Art in New York, depicts a adolescent woman in a field, gazing at a farmhouse on an arcadian summer day.

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But this admirable angel has a aphotic side.

The accountable in the painting is Christina Olson, Wyeth’s acceptable acquaintance and neighbor. For best of her life, she suffered from a abstruse disorder, which boring took abroad her adeptness to walk, and eventually to use her hands. She died at the age of 74 afterwards a difficult life, and her ache has never been diagnosed.

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Until now.

After carefully analytical a ambit of affirmation about her condition, Mayo Clinic adolescent neurologist Marc Patterson has pinpointed a diagnosis. He thinks she acceptable had an early-onset anatomy of Charcot-Marie-Tooth Disease, a accumulation of affiliated disorders that affect the borderline fretfulness and can advance to cogent problems with movement. He will bear his analysis at the 23nd anniversary Actual Clinicopathological Conference, captivated Friday, May 6 at the University of Maryland School of Medicine. The appointment is adherent to the analysis of disorders that afflicted actual figures; in the past, experts accept focused on the diseases of luminaries such as Lenin, Darwin and Lincoln.

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Dr. Patterson, a assistant of neurology, pediatrics and medical analysis at the Mayo Clinic in Rochester, Minnesota, advised her medical history, and additionally advised Wyeth’s art that portrayed her, including Christina’s World.

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“This was a alluring case,” he says. “This painting has continued been a admired of mine, and the catechism of Christina’s ailment was an arresting medical mystery. I anticipate her case best fits the contour of this disease.”

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Also speaking at the appointment will be Thomas B. Cole, accessory editor for the Journal of the American Medical Association. Dr. Cole is an able on art adherent to medical topics.

The appointment was founded in 1995 by Philip A. Mackowiak, MD, Carolyn Frenkil and Selvin Passen History of Anesthetic Scholar-in-Residence at the University of Maryland School of Medicine. “This is a amazing allotment of medical detective work,” says Dr. Mackowiak. “It brings home the actuality that anesthetic has abstruse astronomic amounts in the accomplished few decades.”

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Explore further: Darwin’s campaign may accept led to illness, afterlife

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